The March edition of Elle goes on sale tomorrow, and more than 20 million readers will be reached by the campaign.
The magazine has teamed up with the commercial initiative (Red), which works with well-known brands such as Converse and Gap.
Gisele Bundchen is pictured in a series of poses in support of the (Red) brand which generates money for African Aids programmes
The 28-year-old Brazilian is pictured in a series of poses, including one where she is painting and another where she is eating spaghetti, which will appear in some 30 editions of the magazine.
She said: 'I grew up in a country strongly affected by poverty.
On street corners you see kids doing things on the wrong side of the law.
'The face of suffering isn't an abstract thing for me, and I've always said to myself that if I could do something to help, I would.
The 28-year-old said she wanted to do something to help the cause
'Follow your instincts and your heart: if you are able to buy and help others at the same time, why deny yourself the pleasure?'
(Red) is a brand created in 2006 by Bono and Bobby Shriver.
Money is generated through its partners, who design and sell specific products and contribute a share of the profits to invest in African Aids programmes.
The photoshoot is being carried in some 30 editions of Elle magazine
Gisele disappointed her male fans across the globe last month after becoming engaged to American footballer Tom Brady.
Ever the romantic, Brady got down on bended knee with a diamond solitaire ring and proposed to the beauty in Los Angeles.
The couple are said to be discussing a huge wedding in the spring or a more intimate and quicker ceremony in Costa Rica, where Gisele has a home.
Brady's proposal came after months of speculation the couple were planning to wed.
Gisele and Brady, 31, started dating in December 2006 - just weeks after the New England Patriots quarterback ended his three year relationship with I, Robot actress Bridget Moynahan.
Just a few months into his relationship with Bundchen, Brady was surprised to learn Moynahan was pregnant with his child. She gave birth to their son John Edward Thomas Moynahan in August 2007.
Despite their split, Brady and Moynahan remain on speaking terms and 17-month-old John spends time with his father and Bundchen.
Gisele is the highest paid supermodel in the world, with an estimated salary of £17.5million in 2007.
Before dating Brady, she had a high-profile on/off romance with actor Leonardo DiCaprio until 2005.
